Astaxanthin protects β-cells against glucose toxicity in diabetic db/db mice

@article{Uchiyama2002AstaxanthinP,
  title={Astaxanthin protects $\beta$-cells against glucose toxicity in diabetic db/db mice},
  author={K. Uchiyama and Y. Naito and G. Hasegawa and N. Nakamura and Jiro Takahashi and T. Yoshikawa},
  journal={Redox Report},
  year={2002},
  volume={7},
  pages={290 - 293}
}
Oxidative stress induced by hyperglycemia possibly causes the dysfunction of pancreatic -cells and various forms of tissue damage in patients with diabetes mellitus. [...] Key Method We used diabetic C57BL/KsJ-db/db mice and db/m for the control. Astaxanthin treatment was started at 6 weeks of age and its effects were evaluated at 10, 14, and 18 weeks of age by non-fasting blood glucose levels, intraperitoneal glucose tolerance test including insulin secretion, and -cell histology. The non-fasting blood glucose…Expand
Astaxanthin alleviates gestational diabetes mellitus in mice through suppression of oxidative stress
Astaxanthin protects mesangial cells from hyperglycemia‐induced oxidative signaling
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