Astaxanthin protects β-cells against glucose toxicity in diabetic db/db mice

@inproceedings{Uchiyama2002AstaxanthinP,
  title={Astaxanthin protects β-cells against glucose toxicity in diabetic db/db mice},
  author={Kazuhiko Uchiyama and Yuji Naito and Goji Hasegawa and Naoto Nakamura and Jiro Takahashi and Toshikazu Yoshikawa},
  year={2002}
}
Oxidative stress induced by hyperglycemia possibly causes the dysfunction of pancreatic -cells and various forms of tissue damage in patients with diabetes mellitus. Astaxanthin, a carotenoid of marine microalgae, is reported as a strong anti-oxidant inhibiting lipid peroxidation and scavenging reactive oxygen species. The aim of the present study was to examine whether astaxanthin can elicit beneficial effects on the progressive destruction of pancreatic -cells in db/db mice ‐ a well-known… CONTINUE READING

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