Assumptions and validations of statistical tests for functional neuroimaging.

  title={Assumptions and validations of statistical tests for functional neuroimaging.},
  author={Per E. Roland and Bal{\'a}zs Guly{\'a}s},
  journal={The European journal of neuroscience},
  volume={8 11},
We contrast two statistical methods: three-dimensional cluster analysis and statistical parametric mapping. We show that three-dimensional cluster analysis is based on a neurobiological theory of the regulation of blood flow and, unlike statistical parametric mapping, carries a minimum of assumptions that are tested. Statistical parametric mapping is a formal approach, which is based on a multitude of assumptions of which the majority have not been validated. We also demonstrate that in… CONTINUE READING