Assoziationsstudien von Polymorphismen zur Risikoevaluierung in der Schwangerschaft: Literaturübersicht und Metaanalyse

@article{Tempfer2004AssoziationsstudienVP,
  title={Assoziationsstudien von Polymorphismen zur Risikoevaluierung in der Schwangerschaft: Literatur{\"u}bersicht und Metaanalyse},
  author={C. Tempfer and C. Schneeberger and E.-K. Riener and L. Hefler and C. Keck},
  journal={Geburtshilfe Und Frauenheilkunde},
  year={2004},
  volume={64},
  pages={1080-1089}
}
Polymorphisms are a potentially useful tool for assessing the individual physiology and risk profile of pregnancy-associated disorders. Associations between selected polymorphisms and preeclampsia and thrombosis have been evaluated in over 60 studies. We performed a meta-analysis of 22,11, and 10 association studies and demonstrated that presence of the F-V-Leiden G1691A (OR 1.9; 95% CI 1.6-2.5), the FII G20210A (OR 1.8; 95% CI 1.1-2.9), and the ACT Met235Thr polymorphism (OR 1.6; 95% CI 1.4-1… Expand
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