Associative conditioning of single sensory neurons suggests a cellular mechanism for learning.

@article{Walters1983AssociativeCO,
  title={Associative conditioning of single sensory neurons suggests a cellular mechanism for learning.},
  author={Edgar T Walters and John H. Byrne},
  journal={Science},
  year={1983},
  volume={219 4583},
  pages={405-8}
}
A cellular analog of associative learning has been demonstrated in individual sensory neurons of the tail withdrawal reflex of Aplysia. Sensory cells activated by intracellular current injection shortly before a sensitizing shock to the animal's tail display significantly more facilitation of their monosynaptic connections to a tail motor neuron than cells trained either with intracellular stimulation unpaired to tail shock or with tail shock alone. This associative effect is acquired rapidly… CONTINUE READING

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