Associative Learning Drives the Formation of Silent Synapses in Neuronal Ensembles of the Nucleus Accumbens.

@article{Whitaker2016AssociativeLD,
  title={Associative Learning Drives the Formation of Silent Synapses in Neuronal Ensembles of the Nucleus Accumbens.},
  author={Leslie R Whitaker and Paulo Eduardo Carneiro de Oliveira and Kylie B McPherson and Rebecca Fallon and Cle{\'o}patra da Silva Planeta and Antonello Bonci Bonci and Bruce T Hope},
  journal={Biological psychiatry},
  year={2016},
  volume={80 3},
  pages={246-56}
}
BACKGROUND Learned associations between environmental stimuli and rewards play a critical role in addiction. Associative learning requires alterations in sparsely distributed populations of strongly activated neurons, or neuronal ensembles. Until recently, assessment of functional alterations underlying learned behavior was restricted to global neuroadaptations in a particular brain area or cell type, rendering it impossible to identify neuronal ensembles critically involved in learned behavior… CONTINUE READING
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