Associations of subtypes of hemoglobin with delta-aminolevulinic acid dehydratase genotype and dimercaptosuccinic acid-chelatable lead levels.

@article{Schwartz1997AssociationsOS,
  title={Associations of subtypes of hemoglobin with delta-aminolevulinic acid dehydratase genotype and dimercaptosuccinic acid-chelatable lead levels.},
  author={Brian S. Schwartz and B K Lee and W. Stewart and Kyu Dong Ahn and Karl T. Kelsey and Jan Bressler},
  journal={Archives of environmental health},
  year={1997},
  volume={52 2},
  pages={
          97-103
        }
}
Hemoglobin in erythrocytes may be an important intravascular site of lead binding. We examined associations of hemoglobin subtypes A1 and A2 with delta-aminolevulinic acid dehydratase (ALAD) genotype, a protein that is another important site of erythrocyte lead binding. After oral administration of dimercaptosuccinic acid (DMSA-chelatable lead), we also examined 4-h lead excretion, which provides an estimate of bioavailable lead stores. We randomly selected 57 South Korean current lead battery… CONTINUE READING

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