Associations of primary and secondary organic aerosols with airway and systemic inflammation in an elderly panel cohort.

@article{Delfino2010AssociationsOP,
  title={Associations of primary and secondary organic aerosols with airway and systemic inflammation in an elderly panel cohort.},
  author={Ralph J. Delfino and Norbert Staimer and Thomas K. Tjoa and Mohammad Arhami and Andrea Polidori and Daniel L. Gillen and Steven George and Martin M. Shafer and James J. Schauer and Constantinos Sioutas},
  journal={Epidemiology},
  year={2010},
  volume={21 6},
  pages={892-902}
}
BACKGROUND Exposure-response information about particulate air-pollution constituents is needed to protect sensitive populations. Particulate matter <2.5 mm (PM2.5) components may induce oxidative stress through reactive-oxygen-species generation, including primary organics from combustion sources and secondary organics from photochemically oxidized volatile organic compounds. We evaluated differences in airway versus systemic inflammatory responses to primary versus secondary organic particle… CONTINUE READING
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