Associations of inflammatory markers with AIDS and non-AIDS clinical events after initiation of antiretroviral therapy: AIDS clinical trials group A5224s, a substudy of ACTG A5202.

@article{Mccomsey2014AssociationsOI,
  title={Associations of inflammatory markers with AIDS and non-AIDS clinical events after initiation of antiretroviral therapy: AIDS clinical trials group A5224s, a substudy of ACTG A5202.},
  author={Grace A. Mccomsey and Douglas W. Kitch and Paul Edward Sax and Camlin Tierney and Nasreen C Jahed and Kathleen M Melbourne and Belinda Leung Fung Ha and Todd T. Brown and Anthony Bloom and Neal S. Fedarko and Eric S Daar},
  journal={Journal of acquired immune deficiency syndromes},
  year={2014},
  volume={65 2},
  pages={167-74}
}
BACKGROUND The association of inflammatory biomarkers with clinical events after antiretroviral therapy initiation is unclear. METHODS A5202 randomized 1857 treatment-naive subjects to abacavir/lamivudine or tenofovir-DF/emtricitabine with efavirenz or atazanavir/ritonavir. Substudy A5224s measured inflammatory biomarkers on subjects with available plasma from baseline and week 24 or 96. An exploratory analysis of the association of high-sensitivity C-reactive protein, interleukin-6 (IL-6… CONTINUE READING
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