Associations of genetic variants in ADAM33 and TGF-β1 genes with childhood asthma risk.

@article{Li2014AssociationsOG,
  title={Associations of genetic variants in ADAM33 and TGF-β1 genes with childhood asthma risk.},
  author={Hongbin Li and Yuchun Li and Mingwu Zhang and Guangchui Xu and Xianjun Feng and Jingzhuan Xi and Bing Zhao},
  journal={Biomedical reports},
  year={2014},
  volume={2 4},
  pages={533-538}
}
The aim of the present study was to explore the associations of genetic variants in the ADAM33 and TGF-β1 genes with the risk of childhood asthma. A total of 299 asthmatic children and 311 healthy controls were recruited in the hospital-based case-control study. The asthmatic subjects were further divided into mild and severe groups according to disease severity. Single-nucleotide polymorphisms (SNP) at ADAM33 V4, T2, S2 and T1, and TGF-β1 C-509T and T869C were selected and detected with PCR… CONTINUE READING
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