Associations of circulating C-reactive protein and interleukin-6 with cancer risk: findings from two prospective cohorts and a meta-analysis

@article{Heikkil2008AssociationsOC,
  title={Associations of circulating C-reactive protein and interleukin-6 with cancer risk: findings from two prospective cohorts and a meta-analysis},
  author={Katriina Heikkil{\"a} and Ross Harris and Gordon Lowe and Ann Rumley and John Yarnell and John Gallacher and Y Ben-Shlomo and Shah Ebrahim and Debbie A Lawlor},
  journal={Cancer Causes & Control},
  year={2008},
  volume={20},
  pages={15-26}
}
We investigated the associations of circulating C-reactive protein (CRP) and interleukin-6 (IL-6) with cancer risk. We examined the associations of CRP and IL-6 with incident cancer in two prospective cohorts, the British Women’s Heart and Health Study (4,286 women aged 60–80) and the Caerphilly Cohort (2,398 men aged 45–59) using Cox regression and pooled our findings with previous prospective studies’ in fixed and random effects meta-analyses. CRP and IL-6 were associated with some incident… CONTINUE READING
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