Associations of candidate genes to age-related macular degeneration among racial/ethnic groups in the multi-ethnic study of atherosclerosis.

@article{Klein2013AssociationsOC,
  title={Associations of candidate genes to age-related macular degeneration among racial/ethnic groups in the multi-ethnic study of atherosclerosis.},
  author={Ronald Klein and Xiaohui Li and Jane Z. Kuo and Barbara E. Klein and Mary Frances Cotch and Tien Yin Wong and Kent D. Taylor and Jerome I. Rotter},
  journal={American journal of ophthalmology},
  year={2013},
  volume={156 5},
  pages={1010-1020.e1}
}
PURPOSE To describe the relationships of selected candidate genes to the prevalence of early age-related macular degeneration (AMD) in a cohort of whites, blacks, Hispanics, and Chinese Americans. DESIGN Cross-sectional study. METHODS setting: Multicenter study. study population: A total of 2456 persons aged 45-84 years with genotype information and fundus photographs. procedures: Twelve of 2862 single nucleotide polymorphisms (SNPs) from 11 of 233 candidate genes for cardiovascular disease… CONTINUE READING

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Age-related macular degeneration: genetics and biology coming together.

Annual review of genomics and human genetics • 2014
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