Associations of age with serum insulin, proinsulin and the proinsulin-to-insulin ratio: a cross-sectional study

@inproceedings{Bryhni2010AssociationsOA,
  title={Associations of age with serum insulin, proinsulin and the proinsulin-to-insulin ratio: a cross-sectional study},
  author={Bente Bryhni and Egil Arnesen and Trond Geir Jenssen},
  booktitle={BMC endocrine disorders},
  year={2010}
}
BACKGROUND Insulin responses and insulin levels seem to decline with age. However, the question of beta cell impairment attributable to ageing has been sparsely addressed in population-based studies. Non-fasting insulin levels are determined by the ambient degree of insulin resistance together with the capacity of beta cells to compensate by insulin secretion to prevent hyperglycaemia. A raised proinsulin-to-insulin ratio (proinsulin/insulin) due to impaired processing of proinsulin is an early… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 49 references

The evolution of beta-cell dysfunction and insulin resistance in type 2 diabetes.

European journal of clinical investigation • 2002
View 4 Excerpts
Highly Influenced

Determinants of specific serum insulin concentrations in a general Caucasian population aged 50 to 74 years (the Hoorn Study).

Diabetic medicine : a journal of the British Diabetic Association • 1998
View 4 Excerpts
Highly Influenced

Metabolic syndrome and the menopause.

Menopause international • 2008
View 1 Excerpt

Sex differences in the control of glucose homeostasis.

Current opinion in clinical nutrition and metabolic care • 2008
View 2 Excerpts

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