Associations of adiponectin and leptin with stage and grade of PSA-detected prostate cancer: the ProtecT study

@article{Burton2012AssociationsOA,
  title={Associations of adiponectin and leptin with stage and grade of PSA-detected prostate cancer: the ProtecT study},
  author={Anya J Burton and Richard M. Martin and Jeff M. P. Holly and Janet Athene Lane and Jenny L Donovan and Freddie Hamdy and David E. Neal and Kate Tilling},
  journal={Cancer Causes & Control},
  year={2012},
  volume={24},
  pages={323-334}
}
Obesity has been associated with an increased risk of advanced and fatal prostate cancer; adipokines may mediate this association. We examined associations of the adipokines leptin and adiponectin with the stage and grade of PSA-detected prostate cancer. We conducted a nested case–control study comparing 311 men with mainly locally advanced (≥T3, N1, or M1 cases) vs. 413 men with localized (T ≤2 & NX-0 & M0 controls) PSA-detected prostate cancer, recruited 2001–2009 from 9 UK regions to the… CONTINUE READING
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