Associations between white matter hyperintensities and cognitive decline over three years in non-dementia older adults with memory complaints

@article{Moon2017AssociationsBW,
  title={Associations between white matter hyperintensities and cognitive decline over three years in non-dementia older adults with memory complaints},
  author={So Young Moon and Philipe de Souto Barreto and Marie Chupin and Jean François Mangin and for the Maptdsa group},
  journal={Journal of the Neurological Sciences},
  year={2017},
  volume={379},
  pages={266-270}
}
We investigated whether the baseline level and overtime changes of white matter hyperintensities (WMH) would be associated with cognitive decline over three years in non-demented older adults with memory complaints. 109 participants with baseline magnetic resonance imaging (MRI) and follow-up cognitive assessments up to 3-year were included; among them, 82 also had a follow-up MRI assessment over three years. WMH volume was obtained by an automated segmentation algorithm. Baseline WMH volumes… CONTINUE READING

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