Associations between single-nucleotide polymorphisms of the VEGF gene and long-term prognosis of oral squamous cell carcinoma.

@article{Kmmerer2013AssociationsBS,
  title={Associations between single-nucleotide polymorphisms of the VEGF gene and long-term prognosis of oral squamous cell carcinoma.},
  author={Peer Wolfgang K{\"a}mmerer and Felix Peter Koch and Eik Schiegnitz and Vinay V Kumar and Manfred Berres and Takeshi Toyoshima and Bilal Al-Nawas and Juergen Brieger},
  journal={Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology},
  year={2013},
  volume={42 5},
  pages={374-81}
}
INTRODUCTION Functional polymorphisms (SNPs) of the vascular endothelial growth factor (VEGF) are associated with the incidence of oral squamous cell carcinoma (OSCC). An impact of VEGF-SNPs on prognosis of OSCC patients seems possible. Therefore, correlations between prognostic parameters of OSCC patients and five VEGF-SNPs were determined. MATERIALS AND METHODS In a retrospective long-term study, in 113 OSCC patients that underwent curative resections, five VEGF-SNPs (-1154 G/A, +405 G/C… CONTINUE READING

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