Associations between polymorphisms in the vitamin D receptor and breast cancer risk.

@article{Chen2005AssociationsBP,
  title={Associations between polymorphisms in the vitamin D receptor and breast cancer risk.},
  author={Wendy Y. Chen and Elizabeth R. Bertone-Johnson and David J. Hunter and Walter C Willett and Susan E. Hankinson},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2005},
  volume={14 10},
  pages={2335-9}
}
Biological and epidemiologic data suggest that vitamin D levels may influence breast cancer development. The vitamin D receptor (VDR) is a crucial mediator for the cellular effects of vitamin D and additionally interacts with other cell-signaling pathways that influence cancer development. Because functional data exist on FOK1 and previous studies have suggested a relation between BSM1 and breast cancer risk, we evaluated the associations of the FOK1 and BSM1 VDR polymorphisms and breast cancer… CONTINUE READING

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