Associations between pituitary imaging abnormalities and clinical and biochemical phenotypes in children with congenital growth hormone deficiency: data from an international observational study.

@article{Deal2013AssociationsBP,
  title={Associations between pituitary imaging abnormalities and clinical and biochemical phenotypes in children with congenital growth hormone deficiency: data from an international observational study.},
  author={Cheri L. Deal and Caroline Louise Hasselmann and Roland W. Pf{\"a}ffle and Alan G. Zimmermann and Charmian A. Quigley and Christopher Jeremy Child and Elena P. Shavrikova and Gordon B. Cutler and Werner Friedrich Blum},
  journal={Hormone research in paediatrics},
  year={2013},
  volume={79 5},
  pages={283-92}
}
BACKGROUND/AIMS Magnetic resonance imaging (MRI) is used to investigate the etiology of growth hormone deficiency (GHD). This study examined relationships between MRI findings and clinical/hormonal phenotypes in children with GHD in the observational Genetics and Neuroendocrinology of Short Stature International Study, GeNeSIS. METHODS Clinical presentation, hormonal status and first-year GH response were compared between patients with pituitary imaging abnormalities (n = 1,071), patients… CONTINUE READING