Associations between null mutations in GSTT1 and GSTM1, the GSTP1 Ile105Val polymorphism, and mortality in breast cancer survivors

@inproceedings{Duggan2013AssociationsBN,
  title={Associations between null mutations in GSTT1 and GSTM1, the GSTP1 Ile105Val polymorphism, and mortality in breast cancer survivors},
  author={Catherine Duggan and Rachel Ballard-Barbash and Richard Baumgartner and Kathy B. Baumgartner and Leslie Bernstein and Anne Mctiernan},
  booktitle={SpringerPlus},
  year={2013}
}
PURPOSE Here we assessed associations between null mutations in glutathione-S-transferase (GST)T1 and GSTM1 genes, and the rs1695 polymorphism in GSTP1 (Ile(105)Val), and risk of breast cancer-specific (n=45) and all-cause (n=99) mortality in a multiethnic, prospective cohort of 533 women diagnosed with stage I-IIIA breast cancer in 1995-1999, enrolled in the Health, Eating, Activity, and Lifestyle (HEAL) Study. METHODS We measured the presence of the null mutation in GSTT1 and GSTM1, and the… CONTINUE READING
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