Associations between matrix metalloproteinase-8 and -14 and myeloperoxidase in gingival crevicular fluid from subjects with progressive chronic periodontitis: a longitudinal study.

@article{Hernndez2010AssociationsBM,
  title={Associations between matrix metalloproteinase-8 and -14 and myeloperoxidase in gingival crevicular fluid from subjects with progressive chronic periodontitis: a longitudinal study.},
  author={Marcela Hern{\'a}ndez and Jorge A Gamonal and Taina I Tervahartiala and P{\"a}ivi M{\"a}ntyl{\"a} and Oriana Rivera and Andrea Dezerega and Nicol{\'a}s Dutzan and Timo Sorsa},
  journal={Journal of periodontology},
  year={2010},
  volume={81 11},
  pages={1644-52}
}
BACKGROUND Matrix metalloproteinase (MMP)-8 is a central mediator in chronic periodontitis. MMP-8 can be activated by the cooperative action of other MMPs such as MMP-14, reactive oxygen species, and microbial proteases. The aim of this study is to associate the levels, molecular forms, isoenzyme distribution, and degree of activation of MMP-8 and -14, myeloperoxidase (MPO), and tissue inhibitor of MMP (TIMP)-1 in gingival crevicular fluid (GCF) from patients with progressive periodontitis at… CONTINUE READING

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Proteolytic roles of matrix metalloproteinase (MMP)-13 during progression of chronic periodontitis: Initial evidence for MMP-13/MMP-9 activation cascade

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