Associations between human herpesvirus-6, human papillomavirus and cervical cancer.

  title={Associations between human herpesvirus-6, human papillomavirus and cervical cancer.},
  author={E. Susan Amirian and Karen Adler‐Storthz and Michael E. Scheurer},
  journal={Cancer letters},
  volume={336 1},

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  • 2002
Links between human papillomaviruses (HPVs) and cervical cancer were first suspected almost 30 years ago. DNA of specific HPV types has since been found in almost all cervical cancer biopsies. HPV
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    Clinical Microbiology Reviews
  • 2003
Currently, the clearest role for HPV DNA testing is to improve diagnostic accuracy and limit unnecessary colposcopy in patients with borderline or mildly abnormal cytologic test results.
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Papillomaviruses and potential copathogens.
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