Associations between dopamine D2-receptor binding and cognitive performance indicate functional compartmentalization of the human striatum

@article{Cervenka2008AssociationsBD,
  title={Associations between dopamine D2-receptor binding and cognitive performance indicate functional compartmentalization of the human striatum},
  author={Simon Cervenka and Lars B{\"a}ckman and Zsolt Csel{\'e}nyi and Christer Halldin and Lars Farde},
  journal={NeuroImage},
  year={2008},
  volume={40 3},
  pages={1287-95}
}
Based on pharmacological, neuroanatomical, and lesion studies in animals, a functional compartmentalization of the striatal complex has been proposed. However, this has not been convincingly demonstrated in human subjects. Most functions ascribed to the striatum have been linked to its dense dopaminergic innervation, from motor control to higher-order brain functions (e.g., cognition), making the dopamine system a suitable probe for striatal function. Limbic striatum, a region involved in… CONTINUE READING
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