Associations between cerebrospinal fluid biomarkers and long-term neurologic outcome in dogs with acute intervertebral disk herniation.

@article{Witsberger2012AssociationsBC,
  title={Associations between cerebrospinal fluid biomarkers and long-term neurologic outcome in dogs with acute intervertebral disk herniation.},
  author={Tige H Witsberger and Jonathan M. Levine and Geoffrey T Fosgate and Margaret R. Slater and Sharon C. Kerwin and Karen E. Russell and Gwendolyn J. Levine},
  journal={Journal of the American Veterinary Medical Association},
  year={2012},
  volume={240 5},
  pages={
          555-62
        }
}
OBJECTIVE To examine associations between CSF biomarkers, initial neurologic dysfunction, and long-term ambulatory outcome in dogs with acute intervertebral disk herniation (IVDH). DESIGN Prospective clinical study. ANIMALS 54 dogs with acute thoracolumbar IVDH and 16 clinically normal dogs. PROCEDURES For each dog, variables, including CSF myelin basic protein (MBP), lactate, calcium, glucose, and total protein concentrations; nucleated cell count; and creatine kinase (CK) and aspartate… CONTINUE READING

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