Associations between central and peripheral measures of phospholipid breakdown revealed by cerebral 31-phosphorus magnetic resonance spectroscopy and fatty acid composition of erythrocyte membranes

@article{Richardson2001AssociationsBC,
  title={Associations between central and peripheral measures of phospholipid breakdown revealed by cerebral 31-phosphorus magnetic resonance spectroscopy and fatty acid composition of erythrocyte membranes},
  author={Alexandra J. Richardson and Stephen J Allen and Joseph V. Hajnal and I Jane Cox and Basant K. Puri},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2001},
  volume={25},
  pages={1513-1521}
}
1. Abnormal neuronal membrane phospholipid metabolism is increasingly recognized as being of central importance to a number of neuropsychiatric disorders. Currently, two important indices of membrane phospholipid metabolism tend to be measured: the ratio of the areas of the phosphomonoester (PME) and phosphodiester (PDE) peaks from in vivo cerebral phosphorus magnetic resonance spectroscopy (31P MRS) studies; and erythrocyte membrane fatty acid concentrations. Thus far, there have been no… CONTINUE READING

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