Associations between amyloid β and white matter hyperintensities: A systematic review

@article{Roseborough2017AssociationsBA,
  title={Associations between amyloid $\beta$ and white matter hyperintensities: A systematic review},
  author={A. Roseborough and J. Ramirez and S. Black and J. Edwards},
  journal={Alzheimer's \& Dementia},
  year={2017},
  volume={13},
  pages={1154-1167}
}
This systematic review synthesizes current evidence for associations between cortical amyloid β, visualized on amyloid positron emission tomography imaging, and white matter hyperintensity (WMH) burden on magnetic resonance imaging in healthy elderly adults and individuals with cognitive impairment and dementia. 
View on Elsevier
doi.org
34 Citations
Highly Influential Citations
1
Background Citations
9
Results Citations
4

34 Citations

Citation Type

Citation Type

Small vessel disease lesion type and brain atrophy: The role of co‐occurring amyloid
Rates of age- and amyloid β-associated cortical atrophy in older adults with superior memory performance
White matter alterations in Alzheimer’s disease without concomitant pathologies
CSF amyloid is a consistent predictor of white matter hyperintensities across the disease course from aging to Alzheimer's disease
White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities
Brain amyloid β, cerebral small vessel disease, and cognition
Topographic patterns of white matter hyperintensities are associated with multimodal neuroimaging biomarkers of Alzheimer’s disease
Deep White Matter Lesions Are Associated with Early Recognition of Dementia in Alzheimer's Disease.
Coexistence of Cerebral Microbleeds and Amyloid Pathology in Patients with Cognitive Complaints
White matter hyperintensities and CSF Alzheimer disease biomarkers in preclinical Alzheimer disease
...
1
2
3
4
...

References

SHOWING 1-10 OF 107 REFERENCES
Cerebral amyloid angiopathy burden associated with leukoaraiosis: A positron emission tomography/magnetic resonance imaging study
White matter lesion load is associated with resting state functional MRI activity and amyloid pet but not FDG in mild cognitive impairment and early alzheimer's disease patients
APOE ε4 and risk for Alzheimer's disease: Do regionally distributed white matter hyperintensities play a role?
White matter hyperintensities and cerebral amyloidosis: necessary and sufficient for clinical expression of Alzheimer disease?
Pathogenesis of cerebral microbleeds: In vivo imaging of amyloid and subcortical ischemic small vessel disease in 226 individuals with cognitive impairment
Amyloid burden, cerebrovascular disease, brain atrophy, and cognition in cognitively impaired patients
Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly
White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network
Periventricular hyperintensities are associated with elevated cerebral amyloid
White matter microstructural changes in pure Alzheimer's disease and subcortical vascular dementia
...
1
2
3
4
5
...