Associations between Polygenic Risk for Psychiatric Disorders and Substance Involvement

@article{Carey2016AssociationsBP,
  title={Associations between Polygenic Risk for Psychiatric Disorders and Substance Involvement},
  author={Caitlin E. Carey and Arpana Agrawal and Kathleen K. Bucholz and Sarah M. Hartz and Michael T Lynskey and Elliot C. Nelson and Laura J. Bierut and Ryan Bogdan},
  journal={Frontiers in Genetics},
  year={2016},
  volume={7}
}
Despite evidence of substantial comorbidity between psychiatric disorders and substance involvement, the extent to which common genetic factors contribute to their co-occurrence remains understudied. In the current study, we tested for associations between polygenic risk for psychiatric disorders and substance involvement (i.e., ranging from ever-use to severe dependence) among 2573 non-Hispanic European–American participants from the Study of Addiction: Genetics and Environment. Polygenic risk… 
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