Associations between HLA class II alleles in a North Indian population.

  title={Associations between HLA class II alleles in a North Indian population.},
  author={R M Vatchala Rani and Marcelo An{\'i}bal Fern{\'a}ndez-Vi{\~n}a and Peter Stastny},
  journal={Tissue antigens},
  volume={52 1},
The HLA DR and DQ class II genes are in strong linkage disequilibrium and recombinaton is quite rare. However, many different DR-DQ haplotypes appear to have developed during evolution, giving rise to a variety of combinations with different distributions in populations. In the present report, 138 subjects from North India were studied for the alleles of HLA-DRB1, DRB3, DRB5, DQB1 and DQA1 loci using PCR-oligotyping. The probable haplotypes were constructed based on two-locus associations… CONTINUE READING

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