Associations between Carotid Artery Plaque Score, Carotid Hemodynamics and Coronary Heart Disease.


BACKGROUND The carotid artery plaque score (PS) is an independent predictor of Coronary Heart Disease (CHD). This study aims to evaluate the combination of PS and carotid hemodynamics to predict CHD. METHODS A total of 476 patients who underwent carotid ultrasonography and coronary angiography were divided into two groups depending on the presence of CHD. PS, carotid intima-media thickness, and carotid blood flow were measured. Receiver operating characteristic curve analysis was performed to establish the best prediction model for CHD presence. RESULTS Age, sex, carotid intima-media thickness of internal carotid artery and carotid bifurcation, PS, peak systolic velocity (PSA) of right internal carotid artery (RICA), and most resistance index data were significantly related with the presence of CHD. The area under the curve for a collective model, which included factors of the PS, carotid hemodynamics and age, was significantly higher than the other model. Age, PS, and PSA of RICA were significant contributors for predicting CHD presence. CONCLUSIONS The model of PS and PSA of RICA has greater predictive value for CHD than PS alone. Adding age to PS and PSA of RICA further improves predictive value over PS alone.

DOI: 10.3390/ijerph121114275

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@article{Zhang2015AssociationsBC, title={Associations between Carotid Artery Plaque Score, Carotid Hemodynamics and Coronary Heart Disease.}, author={Huiping Zhang and Mengxue Liu and Tiantian Ren and Xiangqian Wang and Dandan Liu and Mingliang Xu and LingFei Han and Zewei Wu and Haibo Li and Yu Zhu and Yufeng Wen and Wenjie Sun}, journal={International journal of environmental research and public health}, year={2015}, volume={12 11}, pages={14275-84} }