Associations between Antibodies to a Panel of Plasmodium falciparum Specific Antigens and Response to Sub-Optimal Antimalarial Therapy in Kampala, Uganda

@inproceedings{Keh2012AssociationsBA,
  title={Associations between Antibodies to a Panel of Plasmodium falciparum Specific Antigens and Response to Sub-Optimal Antimalarial Therapy in Kampala, Uganda},
  author={Chris E. Keh and Aashish R. Jha and Bridget K Nzarubara and David E. Lanar and Sheetij Dutta and Michael Theisen and Philip J. Rosenthal and Grant Dorsey and Douglas F Nixon and Bryan Greenhouse},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND Antibodies are important in the control of blood stage Plasmodium falciparum infection. It is unclear which antibody responses are responsible for, or even associated with protection, partly due to confounding by heterogeneous exposure. Assessment of response to partially effective antimalarial therapy, which requires the host to assist in clearing parasites, offers an opportunity to measure protection independent of exposure. METHODS A cohort of children aged 1-10 years in Kampala… CONTINUE READING
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