Association with Amino Acids Does Not Enhance Efficacy of Polymerized Liposomes As a System for Lung Gene Delivery

@inproceedings{Bandeira2016AssociationWA,
  title={Association with Amino Acids Does Not Enhance Efficacy of Polymerized Liposomes As a System for Lung Gene Delivery},
  author={Elga Bandeira and Miqu{\'e}ias Lopes-Pacheco and Nadia S Chiaramoni and D{\'e}bora Maria Cavalcanti Ferreira and Maria J. Fernandez-Ruocco and Mar{\'i}a Jimena Prieto and Tatiana Maron-Gutierrez and Ramiro M. Perrotta and Hugo Caire de Castro-Faria-Neto and Patricia R M Rocco and Silvia Del Valle Alonso and Marcelo Marcos Morales},
  booktitle={Front. Physiol.},
  year={2016}
}
Development of improved drug and gene delivery systems directly into the lungs is highly desirable given the important burden of respiratory diseases. We aimed to evaluate the safety and efficacy of liposomes composed of photopolymerized lipids [1,2-bis-(tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine] associated with amino acids as vectors for gene delivery into the lungs of healthy animals. Lipopolymer vesicles, in particular, are more stable than other types of liposomes. In this study… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS