Association with AflR in Endosomes Reveals New Functions for AflJ in Aflatoxin Biosynthesis

@inproceedings{Ehrlich2012AssociationWA,
  title={Association with AflR in Endosomes Reveals New Functions for AflJ in Aflatoxin Biosynthesis},
  author={Kenneth C. Ehrlich and Brian M. Mack and Qijian Wei and Ping Li and Ludmila V. Roze and Frank B. Dazzo and Jeffrey William Cary and Deepak Bhatnagar and John E. Linz},
  booktitle={Toxins},
  year={2012}
}
Aflatoxins are the most potent naturally occurring carcinogens of fungal origin. Biosynthesis of aflatoxin involves the coordinated expression of more than 25 genes. The function of one gene in the aflatoxin gene cluster, aflJ, is not entirely understood but, because previous studies demonstrated a physical interaction between the Zn2Cys6 transcription factor AflR and AflJ, AflJ was proposed to act as a transcriptional co-activator. Image analysis revealed that, in the absence of aflJ in A… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 50 REFERENCES

HypC is the anthrone oxidase involved in aflatoxin production

  • K. C. Ehrlich, P. Li, L. Scharfenstein, P.-K. Chang
  • Appl. Environ. Microbiol
  • 2010
Highly Influential
3 Excerpts

Similar Papers

Loading similar papers…