Association tests based on the principal-component analysis

  title={Association tests based on the principal-component analysis},
  author={Sohee Oh and Taesung Park},
  journal={BMC Proceedings},
  pages={S130 - S130}
Haplotypes are composed of specific combinations of alleles at the several loci on the same chromosome. Because haplotypes incorporate linkage disequilibrium (LD) information from multiple loci, haplotype-based association analyses can provide greater powers than the single-marker analysis in the association studies. However, when we construct haplotypes using many markers simultaneously, we may be confronted with a sparseness problem due to a large number of haplotypes. In this paper, we… CONTINUE READING

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A new look at the statistical model identification

  • H Akaike
  • IEEE Trans Automatic Control
  • 1974
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