Association study of trauma load and SLC6A4 promoter polymorphism in posttraumatic stress disorder: evidence from survivors of the Rwandan genocide.

  title={Association study of trauma load and SLC6A4 promoter polymorphism in posttraumatic stress disorder: evidence from survivors of the Rwandan genocide.},
  author={Iris-Tatjana Kolassa and Verena Ertl and Cindy Eckart and Franka Gl{\"o}ckner and Stephan Kolassa and Andreas Papassotiropoulos and Dominique J.-F. de Quervain and Thomas Elbert},
  journal={The Journal of clinical psychiatry},
  volume={71 5},
OBJECTIVE As exposure to different types of traumatic stressors increases, the occurrence of posttraumatic stress disorder (PTSD) increases. However, because some people exhibit either surprising resilience or high vulnerability, further influencing factors have been conjectured, such as gene-environment interactions. The SLC6A4 gene, which encodes serotonin transporter, has been identified as predisposing toward differential emotional processing between genotypes of its promoter polymorphism… 

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