Association study of the single nucleotide polymorphisms in adiponectin-associated genes with type 2 diabetes in Han Chinese.

@article{Wang2009AssociationSO,
  title={Association study of the single nucleotide polymorphisms in adiponectin-associated genes with type 2 diabetes in Han Chinese.},
  author={Yabing Wang and Di Zhang and Yun Liu and Yifeng Yang and Teng Zhao and Jie Xu and Sheng Li and Zuofeng Zhang and Guoyin Feng and Lin He and He Xu},
  journal={Journal of genetics and genomics = Yi chuan xue bao},
  year={2009},
  volume={36 7},
  pages={417-23}
}
Single-nucleotide polymorphisms (SNPs) of ADIPOQ, ADIPOR1, and ADIPOR2 have been associated with type 2 diabetes mellitus (T2DM), but there are many conflicting results especially in Chinese populations. To investigate the contribution of the adiponectin genes and their receptors to T2DM, a case-control study was performed and 11 SNPs of ADIPOQ, ADIPOR1, and ADIPOR2 were genotyped in 985 T2DM and 1,050 control subjects. rs16861194 (-11426 A>G) in the putative promoter of ADIPOQ was associated… CONTINUE READING

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