Association study of the serotoninergic system in migraine in the Spanish population.

@article{Corominas2010AssociationSO,
  title={Association study of the serotoninergic system in migraine in the Spanish population.},
  author={Roser Corominas and Mar{\'i}a Jes{\'u}s Sobrido and Marta Ribas{\'e}s and Ester Cuenca-Le{\'o}n and Patricia Blanco-Arias and Bernat Narberhaus and Manuel Roig and Rogelio Leira and Javier L{\'o}pez-Gonz{\'a}lez and Alfons Macaya and Bru Cormand},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  year={2010},
  volume={153B 1},
  pages={177-84}
}
In order to evaluate the contribution of 19 serotonin-related genes to the susceptibility to migraine in a Spanish population we performed a case-control association study of 122 single nucleotide polymorphisms (SNPs), selected according to genetic coverage parameters, in 528 migraine patients -308 with migraine without aura (MO) and 220 with migraine with aura (MA)- and 528 sex-matched migraine-free controls. The single-marker analysis identified nominal associations with the migraine… CONTINUE READING

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In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
In order to evaluate the contribution of 19 serotonin - related genes to the susceptibility to migraine in a Spanish population we performed a case - control association study of 122 single nucleotide polymorphisms ( SNPs ) , selected according to genetic coverage parameters , in 528 migraine patients -308 with migraine without aura ( MO ) and 220 with migraine with aura ( MA)- and 528 sex - matched migraine - free controls .
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