Association study of the p53-gene Pro72Arg polymorphism in schizophrenia

@article{Chiu2001AssociationSO,
  title={Association study of the p53-gene Pro72Arg polymorphism in schizophrenia},
  author={Hsien-Jane Chiu and Ying-Chieh Wang and J. Chen and C. li Hong and Shan P. Tsai},
  journal={Psychiatry Research},
  year={2001},
  volume={105},
  pages={279-283}
}
The p53 tumor-suppressor gene, encoding a phosphoprotein, is a key element in maintaining genomic stability and cell apoptosis. It is also implicated in nervous-system development. In order to examine the role of the p53 gene for the pathogenesis of schizophrenic disorders, patients (n=155) and control subjects (n=168) were genotyped for the p53-Pro72Arg polymorphism. The results demonstrated no association with schizophrenia and/or age of onset for this polymorphism. 
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