Association study of the I/D polymorphism and plasma angiotensin-converting enzyme (ACE) as risk factors for stent restenosis.

@article{Ribichini2004AssociationSO,
  title={Association study of the I/D polymorphism and plasma angiotensin-converting enzyme (ACE) as risk factors for stent restenosis.},
  author={Flavio Luciano Ribichini and Valeria Ferrero and Giuseppe Matullo and Mauro Feola and Antonello Vado and Terenzio Camilla and Simonetta Guarrera and Sonia Carturan and Corrado Vassanelli and Eugenio Uslenghi and Alberto Piazza},
  journal={Clinical science},
  year={2004},
  volume={107 4},
  pages={381-9}
}
The ID (insertion/deletion) polymorphism of the ACE (angiotensin-converting enzyme) gene controls plasma ACE levels. Both have been correlated with ISR (in-stent restenosis) in preliminary analyses, but not confirmed in larger studies. In the present study, baseline and 6-month quantitative coronary analysis were performed in 897 patients who had stent implantation and the ID polymorphism genotyped. Plasma ACE levels were measured in 848 patients (95%). Restenosis rates among genotypes were 31… CONTINUE READING
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Lescol intervention prevention study investigators. Fluvastatin for prevention of cardiac events following successful first percutaneous coronary intervention: a randomized controlled trial

  • P. W. Serruys, P. de Feyter, C Macaya
  • JAMA, J. Am. Med. Assoc
  • 2002

Current perspective : instent restenosis

  • F. Ribichini
  • Ital . Heart J .
  • 2001

Predictors of coronary in-stent restenosis: importance of angiotensin-converting enzyme gene polymorphism and treatment with angiotensin-converting enzyme inhibitors

  • E. Jorgensen, H. Kelbaek, S Helqvist
  • J. Am. Coll. Cardiol
  • 2001

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