Association study of a novel functional polymorphism of the serotonin transporter gene in bipolar disorder and suicidal behaviour

@article{Luca2005AssociationSO,
  title={Association study of a novel functional polymorphism of the serotonin transporter gene in bipolar disorder and suicidal behaviour},
  author={Vincenzo De Luca and Subi Tharmalingam and Nicole King and John Strauss and Natalie L. Bulgin and James L Kennedy},
  journal={Psychopharmacology},
  year={2005},
  volume={182},
  pages={128-131}
}
A serotonin transporter gene linked polymorphic region (5-HTTLPR) has been investigated in several genetic association studies, including studies of bipolar disorder (BD) and suicidality. The current study was designed to examine whether the new long (A/G) variant polymorphism of the 5-HTT gene may be associated with the suicide attempts in 305 families with at least one member having BD. No association with history of suicide attempt was found either in the multiallelic HTTLPR (LRS=0.15, df=2… CONTINUE READING