Association study of TREM2 polymorphism rs75932628 with late-onset Alzheimer's disease in Chinese Han population.

@article{Ma2014AssociationSO,
  title={Association study of TREM2 polymorphism rs75932628 with late-onset Alzheimer's disease in Chinese Han population.},
  author={Jianfang Ma and Yi Zhou and Jun Xu and Xiaohong Liu and Ying Wang and Yulei Deng and Gang Wang and Wei Xu and Rujin Ren and Xiaoying Liu and Yu Zhang and Cheng Wang and Hui-dong Tang and Shengdi Chen},
  journal={Neurological research},
  year={2014},
  volume={36 10},
  pages={894-6}
}
OBJECTIVE We conducted a case-control study to investigate whether TREM2 polymorphism (rs75932628-T) was associated with late onset Alzheimer's disease in Chinese Southern Han population. METHODS PCR-restriction fragment length polymorphism assay was performed to genotype rs75932628 in 279 cases with late onset Alzheimer's diseases patients and 346 control subjects in Shanghai and Nanjing. RESULTS There was no rs75932628-T variant detected in our sample. However, APOEϵ4 was shown closely… CONTINUE READING
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