Association of white-matter lesions with brain atrophy markers: the three-city Dijon MRI study.

@article{Godin2009AssociationOW,
  title={Association of white-matter lesions with brain atrophy markers: the three-city Dijon MRI study.},
  author={Ophelia Godin and Pauline Maillard and Fabrice Crivello and Annick Alp{\'e}rovitch and Bernard Mazoyer and Christophe Tzourio and Carole Dufouil},
  journal={Cerebrovascular diseases},
  year={2009},
  volume={28 2},
  pages={177-84}
}
BACKGROUND Brain atrophy and white-matter lesions (WML) are common features at cerebral MRI of both normal and demented elderly people. In a population-based study of 1,792 elderly subjects aged 65-80 years, free of dementia, who had a cerebral MRI at entry, we investigated the relationship between WML volume and brain atrophy markers estimated by hippocampal, gray matter (GM) and cerebrospinal fluid (CSF) volumes. METHODS An automated algorithm of detection and quantification of WML was… CONTINUE READING
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