Association of white matter hyperintensities and gray matter volume with cognition in older individuals without cognitive impairment

@inproceedings{Arvanitakis2015AssociationOW,
  title={Association of white matter hyperintensities and gray matter volume with cognition in older individuals without cognitive impairment},
  author={Zoe Arvanitakis and Debra A. Fleischman and Konstantinos Arfanakis and Sue E. Leurgans and Lisa L. Barnes and David A. Bennett},
  booktitle={Brain Structure and Function},
  year={2015}
}
Both presence of white matter hyperintensities (WMH) and smaller total gray matter volume on brain magnetic resonance imaging (MRI) are common findings in old age, and contribute to impaired cognition. We tested whether total WMH volume and gray matter volume had independent associations with cognition in community-dwelling individuals without dementia or mild cognitive impairment (MCI). We used data from participants of the Rush Memory and Aging Project. Brain MRI was available in 209 subjects… CONTINUE READING
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