Association of weight gain and metabolic syndrome in patients taking clozapine: an 8-year cohort study.

@article{Bai2011AssociationOW,
  title={Association of weight gain and metabolic syndrome in patients taking clozapine: an 8-year cohort study.},
  author={Yamei Bai and Chao-Cheng Lin and Jen-Yeu Chen and Tzu Ting Chen and T. P. Su and Pesus Chou},
  journal={The Journal of clinical psychiatry},
  year={2011},
  volume={72 6},
  pages={751-6}
}
INTRODUCTION Metabolic syndrome is an important side effect associated with clozapine. It has been hypothesized that weight gain contributes to the development of metabolic syndrome, but a direct diabetogenic effect has also been suggested. We conducted an 8-year cohort study to determine the association between weight gain and metabolic parameters among schizophrenic patients taking clozapine. METHOD This study is a retrospective cohort study combining a cross-sectional survey of metabolic… CONTINUE READING