Association of vascular endothelial growth factor, transforming growth factor beta, and interferon gamma gene polymorphisms with proliferative diabetic retinopathy in patients with type 2 diabetes

@inproceedings{Paine2012AssociationOV,
  title={Association of vascular endothelial growth factor, transforming growth factor beta, and interferon gamma gene polymorphisms with proliferative diabetic retinopathy in patients with type 2 diabetes},
  author={Suman Kalyan Paine and Analabha Basu and Lakshmi Kanta Mondal and Aditi Sen and Subhadip Choudhuri and Imran Hussain Chowdhury and Avijit Saha and Gautam Bhadhuri and Ankur Mukherjee and Basudev Bhattacharya},
  booktitle={Molecular vision},
  year={2012}
}
PURPOSE Chronic hyperglycemia and hypoxemia are believed to be causal factors in the development of proliferative diabetic retinopathy (PDR) among individuals with type 2 diabetes. It is hypothesized that formation of new blood vessels in the retina due to prolonged hypoxia is associated with increased expression of several growth factors and angiogenic cytokines. In the present study, we investigated the association of genetic polymorphisms in vascular endothelial growth factor (VEGF… CONTINUE READING
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