Association of tyrosine protein kinase activity with mitochondria in human fibroblasts.

@article{Piedimonte1986AssociationOT,
  title={Association of tyrosine protein kinase activity with mitochondria in human fibroblasts.},
  author={Giuseppe Piedimonte and Lucia Silvotti and Sophie Chamaret and Angelo F. Borghetti and Luc Montagnier},
  journal={Journal of cellular biochemistry},
  year={1986},
  volume={32 2},
  pages={113-23}
}
A tyrosine protein kinase activity has been detected in the mitochondrial fraction purified from human fibroblasts. By enzymatic and sedimentation analysis this activity appeared to be localized in the mitochondrial outer membrane. Mitochondrial tyrosine phosphorylation was strictly dependent on the presence of Mn2+ ions. An inverse relationship between… CONTINUE READING