Association of type 2 diabetes with cyclooxygenase-mediated inflammation and oxidative stress in an elderly population.

@article{Helmersson2004AssociationOT,
  title={Association of type 2 diabetes with cyclooxygenase-mediated inflammation and oxidative stress in an elderly population.},
  author={Johanna Helmersson and Bengt O H Vessby and Anders Larsson and Samar Basu},
  journal={Circulation},
  year={2004},
  volume={109 14},
  pages={1729-34}
}
BACKGROUND Involvement of cyclooxygenase (COX)-mediated inflammation in type 2 diabetes has not been studied, and the association between cytokine-mediated inflammation and diabetes is not fully clarified. METHODS AND RESULTS 15-Keto-dihydro-prostaglandin F2alpha (a metabolite of prostaglandin F2alpha and an indicator of COX-mediated inflammation), high-sensitivity C-reactive protein (CRP), serum amyloid protein A (SAA), 8-iso-PGF2alpha (a nonenzymatic, free radical product of arachidonic… CONTINUE READING