Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer.

@article{Elsaleh2000AssociationOT,
  title={Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer.},
  author={Hany Elsaleh and David Joseph and Fabienne Grieu and Nik Zeps and Nigel S Spry and Barry J Iacopetta},
  journal={Lancet},
  year={2000},
  volume={355 9217},
  pages={1745-50}
}
BACKGROUND Adjuvant chemotherapy can improve 5-year survival in Dukes' C colorectal carcinoma. Improved selection of patients who will respond to adjuvant treatments is required. We investigated whether site of tumour origin, sex, and presence of microsatellite instability (MSI) phenotype were associated with a survival benefit from adjuvant chemotherapy. METHODS We analysed data for 656 consecutive patients with Dukes' C colorectal carcinoma, with median follow-up of 54 months (range 7-104… CONTINUE READING

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