Association of tumor necrosis factor polymorphisms with Guillain-Barré syndrome.

  title={Association of tumor necrosis factor polymorphisms with Guillain-Barr{\'e} syndrome.},
  author={Jing Zhang and Hui Dong and Bin Li and Chun-yan Li and Li Guo},
  journal={European neurology},
  volume={58 1},
It has been reported that the tumor necrosis factor (TNF)alpha promoter polymorphism is associated with autoimmune disease and inflammatory disease. It has also been claimed that this polymorphism may affect TNFalpha expression. We investigated the TNFalpha -308 polymorphism and TNFalpha levels in 79 unrelated Chinese patients with Guillain-Barré syndrome (GBS) and 78 healthy controls using PCR-RFLP and ELISA assay. Patients with GBS were divided into 2 subgroups, acute inflammatory… CONTINUE READING
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