Association of tumor necrosis factor-{alpha} gene polymorphisms with advanced stage endometriosis.

@article{Lee2008AssociationOT,
  title={Association of tumor necrosis factor-\{alpha\} gene polymorphisms with advanced stage endometriosis.},
  author={Gyoung Hoon Lee and Young Min Choi and Sung Hoon Kim and Min A Hong and Sung Tack Oh and Young Taik Lim and Shin Yong Moon},
  journal={Human reproduction},
  year={2008},
  volume={23 4},
  pages={977-81}
}
BACKGROUND This study was performed to investigate whether specific haplotypes and several single nucleotide polymorphisms in the promoter region of the tumor necrosis factor (TNF)-alpha gene are associated with the risk of advanced stage endometriosis in a Korean population. METHODS This study comprised women with (n = 246) or without (n = 248) endometriosis. The TNF:g.[-1031T > C], TNF:g.[-863C > A] and TNF:g.[-857C > T] polymorphism in the TNF-alpha gene were assessed by PCR-restriction… CONTINUE READING
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Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors

  • DA van Heel, IA Udalova, +7 authors DP Jewell
  • Hum Mol Genet
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