Association of the serotonin transporter polymorphism and obsessive‐compulsive disorder: Systematic review

@article{Bloch2008AssociationOT,
  title={Association of the serotonin transporter polymorphism and obsessive‐compulsive disorder: Systematic review},
  author={M. Bloch and A. Landeros-Weisenberger and S. Sen and P. Dombrowski and B. Kelmendi and V. Coric and C. Pittenger and J. Leckman},
  journal={American Journal of Medical Genetics Part B: Neuropsychiatric Genetics},
  year={2008},
  volume={147B}
}
We investigated the association between the long (l) and short (s) alleles of the serotonin transporter polymorphism (5‐HTTLPR) in the promoter region of the SLC6A4 gene and obsessive‐compulsive disorder (OCD) using meta‐analysis to combine all published data from case–control and family based association studies (2,283 cases). In stratified meta‐analysis we investigated whether age of sample (child and adult), ethnicity (Caucasian and Asian) and study design (case–control and family‐based… Expand
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