Association of the microsatellite in the 3' untranslated region of the CD154 gene with rheumatoid arthritis in females from a Spanish cohort: a case-control study

@article{MartnDonaire2007AssociationOT,
  title={Association of the microsatellite in the 3' untranslated region of the CD154 gene with rheumatoid arthritis in females from a Spanish cohort: a case-control study},
  author={Trinidad Mart{\'i}n-Donaire and Ignacio Losada-Fern{\'a}ndez and Gema P{\'e}rez-Chac{\'o}n and {\'I}{\~n}igo R{\'u}a-Figueroa and Celia Erausquin and Antonio Naranjo-Hern{\'a}ndez and S{\'i}lvia Rosado and Florentino Sanchez and Ayoze Garc{\'i}a-Saavedra and Mar{\'i}a Jes{\'u}s Citores and Juan A. Vargas and Paloma Perez-Aciego},
  journal={Arthritis Research & Therapy},
  year={2007},
  volume={9},
  pages={R89 - R89}
}
CD40-CD154 interaction is an important mediator of inflammation and has been implicated in T helper type 1-mediated autoimmune diseases including rheumatoid arthritis (RA). Linkage studies have shown association of markers in the proximity of the CD154 gene. In the present work we investigated whether specific allele variants of the microsatellite in the 3' UTR of the CD154 gene might modulate the risk of RA. The study, in a case-control setting, included 189 patients and 150 healthy controls… CONTINUE READING
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